UNDERSTANDING ARTHRITIS

Axial Spondyloarthritis

Learn more about axial spondyloarthritis, a chronic inflammatory condition that primarily affects the spine and sacroiliac joints, causing pain, stiffness, and reduced mobility.

Axial Spondyloarthritis affects around 1 in every 100 people, or about 3 million people in the U.S., impacting mobility and daily life.

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What are Axial Spondyloarthritis?

Axial spondyloarthritis is a chronic (long-term) autoimmune disease. Normally, the immune system fights infections, but in autoimmune diseases, it attacks a person’s own body. In axial spondyloarthritis, the immune system causes damage to the spine.

Some people with more severe axial spondyloarthritis can see the damage to the joint between the spine and hip bones on an X-ray. This is called radiographic axial spondyloarthritis or ankylosing spondylitis. When the damage isn’t visible on X-ray, it is called non-radiographic axial spondyloarthritis.

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Signs and Symptoms

Most common symptoms

Full body pain and stiffness

Pain or swelling in neck

Extreme tiredness/fatigue

Memory and focus problems

Trouble sleeping/insomnia

Skin or eye inflamation

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Other symptoms

You may have symptoms that last a long time or recur (come back). Other symptoms might include:

• Back pain, often in the lower back and extending to the hips or buttocks. The pain is not sudden, and instead develops over the span of weeks.

• Pain or swelling in neck, shoulders, upper back, ribcage, knees, ankles, heels or toes.

• Movement problems (especially with ankylosing spondylitis)

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