Previous Grant Recipients

2000-2001 Reginald Chukwuocha, Ph.D. UCLA School of Medicine Los Angeles, CA Dr. Chukwuocha's studies of pathogenic anti-phospholipid antibodies (aPLs) in antiphospholipd syndrome (APS) are expected to reveal the genes for aPL that cause disease. If the results show a difference in aPL genes between arthritis patients and...

2000-2001 Anne Stevens, M.D., Ph.D. Fred Hutchinson Cancer Research Center Seattle, WADr. Stevens studied maternal cells (cells passed from mother to child during pregnancy) in healthy children and children with autoimmune diseases. These studies are expected to advance the understanding of immune system development. ...

2000-2001 Rico Buchli, Ph.D. University of California Davis, CA Dr. Buchli studied the molecular and functional characterization of sperm protein Sp17 in rheumatoid arthritis. Learning more about this gene may be helpful in the early detection of RA. ...

2000-2001 Susan Boackle, M.D. University of Colorado Health Sciences Center Denver, CO Dr. Boackle studied the abnormality of antibody-producing B cells in mice with systemic lupus erythematosus. The research may lead to the identification of the genes that cause lupus. ...

2001-2002 Michael Vincent, M.D., Ph.D. Brigham and Women's Hospital Boston, MA Dr. Vincent will be studying the immune system at the molecular level. Specifically, he will identify the regulatory role of human T lymphocytes in the inflammatory process of arthritis, with the goal of defining potential targets...

2001-2002 Sucheta M. Vaingankar, Ph.D. Veterans Medical Research Foundation, UCSD San Diego, CA With aging and/or osteoarthritis, the cartilage in joints calcifies due to crystal deposits that directly provoke inflammation, pain and cartilage degeneration. The major mediator of these crystal deposits is a chemical inorganic pyrophosphate. Dr....

2001-2002 Alla Tsytsykova, Ph.D. The Center for Blood Research (an affiliate of Harvard Medical School) Boston, MA Tumor Necrosis Factor Alpha (TNF-alpha) is a protein responsible for inflammation and, ultimately, cartilage destruction in the joints of individuals with rheumatoid arthritis. Dr. Tsytsykova's project will study how the...

2001-2002 Alan Stern, M.D. McGuire VA Medical Center Richmond, VA Hand Osteoarthritis (OA) is a very common form of osteoarthritis which has a genetic basis. Dr. Stern is conducting a clinical study of two hundred pairs of siblings affected by hand osteoarthritis. By analyzing the clinical and...