Iannis Adamopoulos, D.Phil.

Iannis Adamopoulos, D.Phil.

2011-2012
IL-23 May Be Key to New RA Therapy
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Iannis Adamopoulos, D.Phil.
University of California, Davis
Davis, California

Dissecting the IL-23/IL-17A axis in inflammatory arthritis

Dr. Adamopoulos has been named the 2011 Sontag Foundation Fellow of the Arthritis National Research Foundation, an annual award for innovative and cutting-edge rheumatoid arthritis research. In each of the past 11 years, The Sontag Foundation has utilized ANRF’s expertise to choose and completely fund the grant for a top young researcher studying RA.

This study involves a cytokine identified by Dr. Adamopoulos, interleukin 23 (IL-23), as a key regulator of both joint inflammation and bone destruction in RA. His discovery that abnormal expression of IL-23 causes severe arthritis in mice was recently confirmed in human cells. The next step in his research funded by ANRF is to determine the potential of IL-23 inhibitors as arthritis treatments.

ANRF
Article Author
Arthritis National Research Foundation
arthritisresearch@curearthritis.org

The Arthritis National Research Foundation's mission is to provide initial research funding to brilliant, investigative scientists with new ideas to cure arthritis and related autoimmune diseases. Writing articles about the patients affected and the science being done to find a cure shows why we need to come together to #CureArthritis!

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