Julie Lang, Ph.D.

Julie Lang, Ph.D.


Insuring B Cell Tolerance
Julie Lang, Ph.D.

University of Colorado Health Sciences Center
Denver, CO
The role of CR2 in central and peripheral tolerance

A subset of white blood cells, known as B lymphocytes, is responsible for generating antibodies during an immune response to infection. In normal individuals, the immune system insures that antibodies and immune responses are not directed to self-tissues, a process known as “immune tolerance.” The development of autoantibodies associated with numerous autoimmune diseases, most notably lupus, involves a loss of this B cell tolerance. Dr. Lang’s studies will help elucidate the molecular mechanisms involved in the loss of B cell tolerance leading to autoantibody production, which, in turn, will be important in developing therapies designed to insure B cell tolerance.

Article Author
Arthritis National Research Foundation

The Arthritis National Research Foundation's mission is to provide initial research funding to brilliant, investigative scientists with new ideas to cure arthritis and related autoimmune diseases. Writing articles about the patients affected and the science being done to find a cure shows why we need to come together to #CureArthritis!

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