Elucidating the Mechanism of Receptor Editing
Dr. Benedict’s study centers on the effects of anti-DNA antibodies in systemic lupus erythematosus (SLE or lupus). She will examine genetically engineered mice to study how the immune cells react at the molecular level. The mouse genes have human counterparts and she hopes to use these models to devise strategies for preventing or stopping the damaging effects of anti-DNA production in human lupus patients.