The Role of p21 in regulating IL-6 and MMP in RA
Harris Perlman, Ph.D.
Saint Louis University
St Louis, Missouri
Dr. Perlman has identified a gene, p21 that prevents growth and secretion of pro-inflammatory molecules in rheumatoid arthritis. He is studying the pathways of this gene, trying to determine if it is involved in the induction of RA by examining mice lacking the p21 gene. It is hoped that these data will lead to future therapies employing cell growth inhibitors.