The following is a description of a study from one of the many researchers that our organization has funded.

Fine mapping of the significantly linked SLE susceptibility loci at 1q23-24 in multiethnic groups

Hui Wu, M.D.

UCLA School of Medicine

Los Angeles, California

Systemic Lupus Erythematosus (SLE or lupus) occurs more frequently in families of SLE than in the general population. Dr. Wu observed strong evidence that the long arm of chromosome 1 may contain genetic risk factors for SLE. She narrowed the interval harboring this risk factor and warrants further effort in fine mapping for identification of the putative susceptibility gene(s). An understanding of the genes involved in the development of SLE may provide targets to develop more focused therapy for lupus.
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