2011-2012
The following is a description of a study from one of the many researchers that our organization has funded.

IL-23 May Be Key to New RA Therapy

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Iannis Adamopoulos, D.Phil.
University of California, Davis
Davis, California
Dissecting the IL-23/IL-17A axis in inflammatory arthritis

Dr. Adamopoulos has been named the 2011 Sontag Foundation Fellow of the Arthritis National Research Foundation, an annual award for innovative and cutting-edge rheumatoid arthritis research. In each of the past 11 years, The Sontag Foundation has utilized ANRF’s expertise to choose and completely fund the grant for a top young researcher studying RA.

This study involves a cytokine identified by Dr. Adamopoulos, interleukin 23 (IL-23), as a key regulator of both joint inflammation and bone destruction in RA. His discovery that abnormal expression of IL-23 causes severe arthritis in mice was recently confirmed in human cells. The next step in his research funded by ANRF is to determine the potential of IL-23 inhibitors as arthritis treatments.

You may return to the list of research that we have funded.