The following is a description of a study from one of the many researchers that our organization has funded.

Interleukin-4 Potentiates Peripheral Deletion of Autoreactive Th1 Cells in Proteoglycan-Induced Arthritis

Jian Zhang, M.D.
Rush-Presbyterian – St. Luke’s Medical Center
Chicago, Illinois
Dr. Zhang is studying the mechanism of treating RA with a cytokine called Interleukin-4, which is thought to retard the disease development by inducing apoptosis (death) in harmful T lymphocytes (malfunctioning by attacking self tissues). In normal healthy individuals, the harmful T lymphocytes would be removed by apoptosis, but they remain in RA patients.
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