The following is a description of a study from one of the many researchers that our organization has funded.

Molecular Pathways in Lupus Studied

Maida Wong, M.D.
Los Angeles, California
James Klinenberg Scholar

Programmed death-1-Programmed death-1 ligand (PD-1-PDL-1) pathway in the New Zealand Black x New Zealand white murine model: a molecular approach

Dr. Wong’s research will study the molecular pathway of lupus using a mouse model. Studies have shown that mutation in the gene responsible for this particular pathway results in increased susceptibility to systemic lupus erythematosus (SLE or lupus) in humans and in mice. Dr. Wong will investigate the molecular pathways in three ways. She expects that the results of these tests will provide greater insight to human autoimmunity.

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