Molecular Pathways in Lupus Studied
Programmed death-1-Programmed death-1 ligand (PD-1-PDL-1) pathway in the New Zealand Black x New Zealand white murine model: a molecular approach
Dr. Wong’s research will study the molecular pathway of lupus using a mouse model. Studies have shown that mutation in the gene responsible for this particular pathway results in increased susceptibility to systemic lupus erythematosus (SLE or lupus) in humans and in mice. Dr. Wong will investigate the molecular pathways in three ways. She expects that the results of these tests will provide greater insight to human autoimmunity.