The following is a description of a study from one of the many researchers that our organization has funded.

Increasing RA Drug Efficiency: A Clinical Project

Massimo Bottini, Ph.D.
Sanford-Burnham Medical Research Institute
La Jolla, California
Nanosystem for targeting Treg in vivo

Regulatory T cells (Treg) are an immune cell population that plays an active role in protecting humans against rheumatoid arthritis. The delivery of drugs specifically to Treg to boost their activity is highly desirable since it could lead to more efficient therapies against rheumatoid arthritis. However, there is still no approach to deliver drugs into specific immune cell populations in living animals.

Dr. Massimo Bottini has developed chemically engineered nanoscopic particles which can efficiently and safely bring pharmaceutical and diagnostic agents into selected cells in living animals. In this clinical study, he is targeting drug delivery only to Treg, and he predicts that new approaches and lower doses of drugs can be used, thereby opening new avenues for low-risk treatment and/or prevention of rheumatoid arthritis.

You may return to the list of research that we have funded.
Translate »

Connect with ANRF Today!

Stay up -to-date with the latest arthritis news, stories and info.​

Make a Donation

Make a one-time or recurring donation and know that you are making a difference by funding cutting-edge arthritis research.

Skip to content