Certain cells that respond to self tissues or organs exist in normal humans; however, their activities are controlled by a cell population called regulatory T cells. The deficit and dysfunction of regulatory T cells cause autoimmune diseases. This novel knowledge provides a possibility that regulatory T cells can replace immunosuppressive drugs to treat autoimmune diseases.

Dr. Song Guo Zheng will study the effects of different combinations of regulatory T cells, generating results that will provide guidance to choose optimal combination of regulatory T cells in the therapy for SLE patients.
In Dr. Zheng’s opinion, it is likely that regulatory T cell therapy will one day replace the immunosuppressive drugs currently used to treat autoimmune diseases and for patients who have had organ transplants. The regulatory T cells might be more effective and less toxic.