2006-2007
The following is a description of a study from one of the many researchers that our organization has funded.

The Role of B Cells in RA

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Taras Lyubchenko, Ph.D.
University of Colorado Health Sciences Center
Denver, Colorado
Role of Complement Receptor 2 (CR2/CD21) in B cell receptor signal transduction

Understanding the mechanisms underlying activation of antibody-producing B cells is particularly important in autoimmune diseases such as rheumatoid arthritis. Dr. Taras Lyubchenko’s study will focus on one of the key processes responsible for the contribution of B cells to the course of the autoimmune disease – intracellular signaling mechanisms. The goal of this study is to characterize these novel mechanisms of B cell activation and to facilitate a new therapeutic approach to reduce B cell activation in rheumatoid arthritis.

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