Yi Liu, Ph.D.
University of Southern California
There are over 100 forms of arthritis. In many instances, patients do not fully express the symptoms of one specific form, but have an overlap of symptoms from two or more diseases. This condition of “overlap” is classified as undifferentiated connective tissue syndrome (UCTS). Dr. Yi Liu has identified several UCTS patients with mutations in the gene which has been identified as regulating cell death. His study hypothesized that defects in this gene may cause an impaired cell death pathway which may contribute to the origination of the disease.