Song Guo Zheng, M.D.

Song Guo Zheng, M.D.

2006-2007

Alternative to Immunosuppressive Drugs
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Song Guo Zheng, M.D.

University of Southern California
Los Angeles, CA
Effects of TGF-beta on both CD4+ and CD8+ cells are required for optimal generation and function of regulatory T cells

Certain cells that respond to self tissues or organs exist in normal humans; however, their activities are controlled by a cell population called regulatory T cells. The deficit and dysfunction of regulatory T cells cause autoimmune diseases. This novel knowledge provides a possibility that regulatory T cells can replace immunosuppressive drugs to treat autoimmune diseases.

Dr. Song Guo Zheng will study the effects of different combinations of regulatory T cells, generating results that will provide guidance to choose optimal combination of regulatory T cells in the therapy for SLE patients.
In Dr. Zheng’s opinion, it is likely that regulatory T cell therapy will one day replace the immunosuppressive drugs currently used to treat autoimmune diseases and for patients who have had organ transplants. The regulatory T cells might be more effective and less toxic.

ANRF
Article Author
Arthritis National Research Foundation
arthritisresearch@curearthritis.org

The Arthritis National Research Foundation's mission is to provide initial research funding to brilliant, investigative scientists with new ideas to cure arthritis and related autoimmune diseases. Writing articles about the patients affected and the science being done to find a cure shows why we need to come together to #CureArthritis!

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