{"id":25265,"date":"2022-04-28T16:00:35","date_gmt":"2022-04-28T16:00:35","guid":{"rendered":"https:\/\/curearthritis.org\/?p=25265"},"modified":"2022-04-30T04:08:45","modified_gmt":"2022-04-30T04:08:45","slug":"2021-22-funded-scientists-recent-research","status":"publish","type":"post","link":"https:\/\/curearthritis.org\/2021-22-funded-scientists-recent-research\/","title":{"rendered":"2021-22 funded scientists recent research"},"content":{"rendered":"\t\t<div data-elementor-type=\"wp-post\" data-elementor-id=\"25265\" class=\"elementor elementor-25265\">\n\t\t\t\t\t\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-29bef338 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"29bef338\" data-element_type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-8c14eeb\" data-id=\"8c14eeb\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t\t\t<div class=\"elementor-element elementor-element-305f9413 elementor-widget elementor-widget-text-editor\" data-id=\"305f9413\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<style>\/*! elementor - v3.16.0 - 12-09-2023 *\/\n.elementor-widget-text-editor.elementor-drop-cap-view-stacked .elementor-drop-cap{background-color:#69727d;color:#fff}.elementor-widget-text-editor.elementor-drop-cap-view-framed .elementor-drop-cap{color:#69727d;border:3px solid;background-color:transparent}.elementor-widget-text-editor:not(.elementor-drop-cap-view-default) .elementor-drop-cap{margin-top:8px}.elementor-widget-text-editor:not(.elementor-drop-cap-view-default) .elementor-drop-cap-letter{width:1em;height:1em}.elementor-widget-text-editor .elementor-drop-cap{float:left;text-align:center;line-height:1;font-size:50px}.elementor-widget-text-editor .elementor-drop-cap-letter{display:inline-block}<\/style>\t\t\t\t<p style=\"margin-bottom: 11px;\"><span style=\"color: #0c3765;\"><span style=\"font-size: 22px;\"><b>2021-22 Grant Recipient Recent Research\u00a0<\/b><\/span><\/span><\/p><p><b>Sarah Baxter, M.D., Ph.D., University of Washington<\/b><\/p><ul><li><a href=\"https:\/\/onlinelibrary.wiley.com\/doi\/abs\/10.1002\/art.41930\" data-cke-saved-href=\"https:\/\/onlinelibrary.wiley.com\/doi\/abs\/10.1002\/art.41930\">International Consensus for the Dosing of Corticosteroids in Childhood-Onset Systemic Lupus Erythematosus With Proliferative Lupus Nephritis<\/a><\/li><li><a href=\"https:\/\/www.sciencedirect.com\/science\/article\/abs\/pii\/S0091674921006102#!\" data-cke-saved-href=\"https:\/\/www.sciencedirect.com\/science\/article\/abs\/pii\/S0091674921006102#!\">Molecular diagnosis of childhood immune dysregulation, polyendocrinopathy, and enteropathy, and implications for clinical management<\/a><\/li><\/ul><p><b>Maria Gutierrez-Arcelus, Ph.D., Boston Children&#8217;s Hospital<\/b><\/p><ul><li><a href=\"https:\/\/www.biorxiv.org\/content\/10.1101\/2022.02.25.481990v1\" data-cke-saved-href=\"https:\/\/www.biorxiv.org\/content\/10.1101\/2022.02.25.481990v1\">Cellular deconstruction of inflamed synovium defines diverse inflammatory phenotypes in rheumatoid arthritis<\/a><\/li><\/ul><p><b>Lauren Henderson, M.D., MMSc,\u00a0Boston Children&#8217;s Hospital<\/b><\/p><p><b>Pui Y Lee, M.D., Ph.D.,\u00a0Boston Children&#8217;s Hospital<\/b><\/p><ul><li><a href=\"https:\/\/www.sciencedirect.com\/science\/article\/abs\/pii\/S0091674921007338\" data-cke-saved-href=\"https:\/\/www.sciencedirect.com\/science\/article\/abs\/pii\/S0091674921007338\">Comprehensive analysis of\u00a0ADA2\u00a0genetic variants and estimation of carrier frequency driven by a function-based approach<\/a><\/li><\/ul><p><b>Ruth J. Napier, Ph.D., Oregon Health &amp; Science University\u00a0<\/b><\/p><ul><li><a href=\"https:\/\/link.springer.com\/article\/10.1186\/s12974-022-02425-x\" data-cke-saved-href=\"https:\/\/link.springer.com\/article\/10.1186\/s12974-022-02425-x\">The innate immune receptor Nlrp12 suppresses autoimmunity to the retina<\/a><\/li><\/ul><p><b>Renuka Nayak, M.D., Ph.D., University of California, San Francisco<\/b><\/p><ul><li><a href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S1931312821005072\" data-cke-saved-href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S1931312821005072\">Human gut bacterial metabolism drives Th17 activation and colitis<\/a><\/li><\/ul><p><b>Michael Paley M.D., Ph.D., Washington University<\/b><\/p><ul><li><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/33851176\/\" data-cke-saved-href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/33851176\/\">Glucocorticoids and B Cell Depleting Agents Substantially Impair Immunogenicity of mRNA Vaccines to SARS-CoV-2<\/a><\/li><\/ul><p><b>Tam Quach, Ph.D., The Feinstein Institutes for Medical Research<\/b><\/p><ul><li><a href=\"https:\/\/insight.jci.org\/articles\/view\/149094?utm_source=notices&amp;utm_medium=email&amp;utm_content=link&amp;utm_campaign=JCI+Insight+-+March+8%2C+2022%2C+issue+published\" data-cke-saved-href=\"https:\/\/insight.jci.org\/articles\/view\/149094?utm_source=notices&amp;utm_medium=email&amp;utm_content=link&amp;utm_campaign=JCI+Insight+-+March+8%2C+2022%2C+issue+published\">Context-dependent induction of autoimmunity by TNF signaling deficiency<\/a><\/li><\/ul><p><b>Nisarg J. Shah, Ph.D., University of California, San Diego<\/b><\/p><ul><li><a href=\"https:\/\/www.biorxiv.org\/content\/10.1101\/2022.01.21.477275v1.abstract\" data-cke-saved-href=\"https:\/\/www.biorxiv.org\/content\/10.1101\/2022.01.21.477275v1.abstract\">Immune-responsive biodegradable scaffolds for enhancing neutrophil regeneration<\/a><\/li><\/ul><p><b>Hu Zeng, Ph.D., Mayo Clinic<\/b><\/p><ul><li><a href=\"https:\/\/europepmc.org\/articles\/pmc8831839\/bin\/table_1.docx\" data-cke-saved-href=\"https:\/\/europepmc.org\/articles\/pmc8831839\/bin\/table_1.docx\">Antigen Specific Humoral and Cellular Immunity Following SARS-CoV-2 Vaccination in ANCA-Associated Vasculitis Patients Receiving B-Cell Depleting Therapy.<\/a><\/li><\/ul><p><b>Shouan Zhu, Ph.D., Ohio University<\/b><\/p><ul><li><p><a href=\"https:\/\/journals.sagepub.com\/doi\/full\/10.1177\/1947603521993209\" data-cke-saved-href=\"https:\/\/journals.sagepub.com\/doi\/full\/10.1177\/1947603521993209\">Sirt5 Deficiency Causes Posttranslational Protein Malonylation and Dysregulated Cellular Metabolism in Chondrocytes Under Obesity Conditions<\/a><\/p><\/li><li><p><a href=\"https:\/\/onlinelibrary.wiley.com\/doi\/abs\/10.1002\/jor.25322\" data-cke-saved-href=\"https:\/\/onlinelibrary.wiley.com\/doi\/abs\/10.1002\/jor.25322\">Obesity promotes lipid accumulation in mouse cartilage\u2014A potential role of acetyl-CoA carboxylase (ACC) mediated chondrocyte de novo lipogenesis<\/a><\/p><\/li><\/ul>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t\t\t\t<\/div>\n\t\t","protected":false},"excerpt":{"rendered":"<p>2021-22 Grant Recipient Recent Research\u00a0 Sarah Baxter, M.D., Ph.D., University of Washington International Consensus for the Dosing of Corticosteroids in Childhood-Onset Systemic Lupus Erythematosus With Proliferative Lupus Nephritis Molecular diagnosis of childhood immune dysregulation, polyendocrinopathy, and enteropathy, and implications for clinical management Maria Gutierrez-Arcelus, Ph.D., Boston Children&#8217;s Hospital Cellular deconstruction of inflamed synovium defines diverse [&hellip;]<\/p>\n","protected":false},"author":2,"featured_media":25275,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[746,747],"tags":[],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v22.5 - 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