CD8+ Treg suppression of collagen-induced arthritisAutoimmune diseases, including Rheumatoid Arthritis (RA), occur when the immune system mistakenly attacks the body’s own tissues. This complex system of cells and antibodies normally destroys “invaders” such as viruses and infections. Unfortunately, RA patients have immune cells and antibodies in their blood that attack their own tissues.
In this project, Dr. Kim evaluates the ability of a recently identified cell population, termed CD8+ regulatory T cells, to suppress or block RA progression. Using novel strategies, Dr. Kim will examine the potential therapeutic effects of this cell-based treatment to ameliorate or prevent RA.