2006-2007
The following is a description of a study from one of the many researchers that our organization has funded.

Cartilage Regeneration Study

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Li Zeng, Ph.D.
Tufts University School of Medicine
Boston, Massachusetts
Nkx3.2 nuclear localization and cartilage formation

Arthritis is a widespread, debilitating disease in which the joint cartilage slowly disintegrates. One of the possible remedies for this disease is to regenerate cartilage and transplant the regenerated tissue to the affected joint. To regenerate cartilage, we need to have a thorough understanding of the mechanisms of how cartilage is formed from progenitor cells. Many of the signaling events in the regeneration process are similar to tissue formation processes in the embryo. Dr. Zeng’s long-range goal is to reveal the mechanisms that control cartilage formation in the embryo to provide knowledge for treating arthritis through cartilage regeneration.

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